Anti-Inflammatory Drops Prodrug NSAID technology

Product Overview

Nepafenac 0.1% ophthalmic suspension for potent topical non-steroidal anti-inflammatory relief of post-surgical ocular pain and inflammation.

About Inflasight Eye Drop

Inflasight Eye Drop contains Nepafenac 0.1% w/v, a topical non-steroidal anti-inflammatory drug (NSAID) with unique prodrug characteristics that enable deep intraocular penetration. Upon corneal absorption, Nepafenac is rapidly converted to its active metabolite Amfenac, which potently inhibits cyclooxygenase (COX-1 and COX-2) enzymes, reducing prostaglandin synthesis at the site of ocular inflammation. This mechanism provides effective control of post-surgical pain and inflammation while maintaining a favorable safety profile compared to topical corticosteroids.

Key Features

  • Prodrug technology for deep ocular penetration
  • Rapid conversion to active metabolite Amfenac
  • Dual COX-1 and COX-2 inhibition
  • Once-daily or three-times-daily dosing flexibility
  • Reduced risk of IOP elevation vs. steroids
  • Steroid-sparing anti-inflammatory action

Benefits

  • Effective pain relief after cataract surgery
  • Reduces post-operative cystoid macular edema
  • Lower risk of steroid-related complications
  • Faster visual recovery after intraocular procedures
  • Convenient dosing regimen
  • Excellent intraocular tolerability

Technical Specifications

CompositionNepafenac 0.1% w/v (1 mg/mL)
Volume5 mL per bottle
pH Range6.5 - 7.5
Dosage FormOphthalmic suspension
StorageStore at 2-25°C. Do not freeze.
Shelf Life24 months from date of manufacture
Packaging5 mL sterile ophthalmic suspension bottle
Dosage1 drop in the affected eye(s) three times daily beginning 1 day prior to surgery and continuing for 2 weeks post-operatively

Applications & Uses

  • Post-cataract surgery pain and inflammation
  • Intraocular lens-induced inflammation
  • Corneal refractive surgery recovery
  • Panretinal photocoagulation inflammation
  • Uveitis-associated anterior segment inflammation
  • Prophylactic anti-inflammatory in intraocular procedures

Available Variants

  • Standard (5 mL) — SKU INF-005
  • Extended Treatment (10 mL) — SKU INF-010

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